vaccination in developing countries: a review of probable factors for lower responses to vaccine

نویسندگان

mohammed-jafar saffar department of pediatric infectious disease, bou ali sina hospital, pasdaran boulevard, sari, iran

hiva saffar tehran university of medical sciences, shariati hospital, tehran, iran

hana saffar tehran university of medical sciences, shariati hospital, tehran, iran

چکیده

abstract prevention of infectious diseases by immunization in children has markedly diminished the morbidity and mortality of once common contagious diseases in many countries worldwide. immunization programs have led to the global eradication of smallpox, elimination of measles and poliomyelitis in regions of the world, and substantial reduction in the morbidity and mortality attributed to diphtheria, tetanus, pertussis, and measles. childhood vaccination was estimated to prevent more than 2.5 million deaths for vaccine preventable- diseases each year. however, at current levels of coverage, it still causes 1.7 million deaths annually, most of them in developing countries. the main objectives of this review are as following: to overview the expanded programme of immunization and who global vision and strategies for vaccination. to review underlying mechanisms that influence host immune response to vaccine, and differentiate primary from secondary vaccine failure. to determine the environmental factors that may reduce the potency of the vaccines or vaccinees. to explain the probable factors that lead to lower responses in vaccine recipients in developing countries.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Factors Affecting the Rate of Pediatric Pneumonia in Developing Countries: a Review and Literature Study

Introduction: Millions of children less than 5 years old die from pneumonia globally and about 75-70% of these deaths occur in infants. Persian and English articles of International and National databases such as “WHO, Scopus and the Cochrane, Pub Med, Science Direct, Wiley, Google Scholar, SID, Iran Medex, Magiran, Med Lib and Iran Doc were searched from 1970 to 2014. Result: The factors such ...

متن کامل

Future competencies for hospital management in developing countries: Systematic review

    Background: This was a systematic review presenting the future competencies for hospital managers.     Methods: Participants, interventions, comparisons and outcomes (PICO) strategy with MeSH terms were used for searching. Databases used were Web of Science, PsycINFO and Medline, EBSCO, ScienceDirect, Emerald, ProQuest, Social Sciences Research Network, Embase, and some Iranian database su...

متن کامل

Rotavirus vaccination in developing countries.

Although two oral rotavirus vaccines are licensed in many countries, multiple factors may affect decision-making regarding introduction into national immunization programs in developing countries. Financial and logistic challenges to introduction of rotavirus vaccines in countries with limited infrastructure and resources are accompanied by a perceived lack of need and evidence from recent vacc...

متن کامل

Responses of cytokines to influenza vaccination in elite boy gymnasts

ABSTRACT Introduction: Many of effects of exercise are mediated through cytokines. Inflammatory cytokines are increased by exercise and inhibited by anti-inflammatory cytokines. Meanwhile, vaccination leads to an increase in the inflammatory cytokines. To test the hypothesis that exercise training might alter the cytokine response to the influenza vaccine, we measured selected cy...

متن کامل

management of lower respiratory tract illnesses in developing countries: a narrative review

pneumonia is the leading cause of mortality in young children worldwide. early diagnosis and empiric antibacterial therapy is an important strategy to improve outcome. the world health organization (who) has developed case management guidelines to reduce pneumonia-related deaths through early diagnosis and antibiotic treatment. for management purpose, pneumonia is subclassified by its severity....

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of pediatrics review

جلد ۱، شماره ۱، صفحات ۱۲-۱۸

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023